Ekstrak Daun Keji Beling (Strobilanthes crispus L.) Uuntuk Penurunan Kadar Kolesterol Pada Tikus Putih Jantan (Ratus norvegicus) Galur Wistar

DOI: https://doi.org/10.21070/medicra.v2i1.1648

Author (s)


(1) * Fadila Abd Rachman   (Universitas Muhammadiyah Sidoarjo)  
        Indonesia
(2)  Syahrul Ardiansyah   (Universitas Muhammadiyah Sidoarjo)  
        Indonesia
(*) Corresponding Author

Abstract


Indonesian citizens have a various lifestyle impacts on the increasing of blood-cholesterol
level. One of the potential herbal medicine is keji beling leaves (Strobilanthes crispus L.)
because of these leaves contains flavonoid and sterol. This study aims to analyze the
efficacy of Strobilanthes crispus L. leaves extract to decrease the blood-cholesterol level.
This research is experimental laboratory with pretest – post test only control group design.
The total of 24 Wistar rats were divided into six groups, as follow: negative control, positive
control, treated with 25%, 50%, 75% and 100% Strobilanthes crispus L. extract. The
therapy was administrated for 14 days. Cholesterol test using POCT method. The data
were analyzed using Repeated Measured Anova. The results showed that Strobilanthes
crispus L. leaves extracts potentially decreased on blood-cholesterol level in Wistar rats
after 14 days of treatment. This study reflected that the Strobilanthes crispus L. leaves
extract can be used as the alternative therapy on the blood-cholesterol level. The greatest
decrease in P4 (100% concentration).



Keywords

ekstrak, keji beling (Strobilanthes crispus L), kolesterol, Rattus norvegicus



Full Text: Untitled



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